Neoantigen Peptide Manufacturing Overview

The use of tumor specific neoantigen peptides used for personalized cancer treatments is growing at an exponential rate. Cancer has historically been treated with invasive surgery, chemotherapy or radiation to remove or destroy cancer cells. Chemotherapy and radiation kill healthy cells along with the intended cancerous and can cause a long list of additional unwanted side effects. Better understanding of genetic mutations has made it possible for patient specific treatments, where the patients own immune system is used to fight their specific cancer. This can be much less invasive and less taxing on the patient than previously mentioned forms of treatment.

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Neoantigen Manufacturing Expertise

vivitide is partnering with customers in the US and Europe to supply the peptides for neoantigen projects. Our agility and reliability are key elements in our relationship with our partners. We understand the urgency required and have developed processes to ensure their success. With turnaround times in as little as 3 weeks, vivitide is committed to ensuring the success of your neoantigen project.

The sequencing of a tumor cell can often provide well over 100 different neoantigen peptides of interest. With this and the likelihood of multiple patients at one time, it is important to ensure that there is ample band width for production of such projects. vivitide’s state of the art high-throughput production facility allows for the production of large orders with rapid turnaround times and high flexibility.


Key Manufacturing Techniques for Neoantigen Peptides

  • Patient segregation throughout manufacturing
  • Fastest turnaround time in as little as 3 weeks
  • High throughput manufacturing capabilities
  • Controlled environment with robust quality systems
  • Strategic approach to hydrophobic and structurally hindered sequences
  • Peptide pooling and aliquoting
  • Greater than 99% individual peptide success rate

Dedicated Project Management

Our highly skilled and dedicated project managers are vital to the successful completion of neoantigen projects. They are devoted to ensuring outstanding communication and collaboration with our customers throughout the entire process, from initial contact to the receipt of the peptides.


Our quality system is specifically designed to ensure the highest quality peptides, batch to batch consistency and reliability, while maintaining our competitive advantage with a fast turnaround time to support the need of our customers.

Our stringent quality controls ensure the delivery of the highest quality peptides. Our quality control generally includes LC-ESI-MS or MALDI-MS and HPLC. Based on the individual requirements of our customers we also provide:

  • Amino Acid Analysis
  • NMR
  • Residual Solvents
  • Net Peptide Content
  • Solubility and Stability Testing
  • Karl Fisher Water Content
  • Solubility Testing
  • Elemental Analysis
  • and More