Amyloid beta (1-42)

Product Name: Amyloid beta (1-42)

Product Number: AA-001

Synonym(s): Abeta; Abeta42

One-Letter-Code: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

Description: Manufactured by AmideBio, LLC.; May require additional lead time, please inquire. Amyloid beta 1-42 (Aβ42) plays a central role in the pathogenesis of Alzheimer’s disease (AD). Recombinant Aβ42 has reproducibly been shown to have higher in vitro toxicity and aggregate significantly faster than synthetically prepared Aβ42 due to the absence of (n-1) deletion products and racemized amino acids that are characteristic of chemical synthesis (Finder, et al., J.Mol. Biol.). Lyophylized.

Molecular Weight (g/mol): 4514.1

Purity: > 99% HPLC, Mass spec

Storage Conditions: -20 °C

Reference(s): B.A. Yankner, et. al., Science, 250, 279 (1990). D.J. Selkoe, Physiol. Rev., 81, 741 (2001). W.B.Stine, et. al., J. Biol. Chem, 278, 11612 (2003).

Special Note(s): For research use ONLY. Not for use on humans.