Product Name: HG1 Toxin
Product Number: AA-016
Application: A Kunitz-Type Scorpion Toxin Specific for mKv1.3/KCNA3 Potassium Channel
Description: Manufactured by AmideBio, LLC.; May require additional lead time, please inquire. Inhibits currents with an IC50 of 6.2 nM (where 1 µM inhibits 80% of currents). Also has weak inhibitory activity against mKv1.1/KCNA1 (where 1 µM inhibits less than 50% of currents), hKv1.2/KCNA2 (where 1 µM inhibits less than 50% of currents), and hKCa2.3/KCNN3. This scorpion toxin has potential for diagnosing and treating Kv1.3-mediated autoimmune diseases. Other toxins and knottins can be synthesized based on your requirement. Lyophylized.;
Molecular Weight (g/mol): 7088.32
Purity: > 99%
Storage Conditions: -20 °C
Reference(s): Chen, et al., J. Bio. Chem.
Special Note(s): For research use ONLY. Not for use on humans.