CoV-2 S1 (1-681)
Product Name CoV-2 S1 (1-681)
Product Number SARS-045
Synonym(s) Coronavirus 2019-nCoV Spike Glycoprotein-S1 (1-681), RecombinantIntroduction A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019.The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans.While bats are probably the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.
Description The HEK293-derived recombinant protein contains the Coronavirus 2019-nCoV Spike Glycoprotein S1, Wuhan-Hu-1 strain, amino acids 1-681 fused to Fc tag at C-terminal having a M.W. of 76 kDa.
Purification Method PNTA Sepharose-Affinity Purification
Formulation CoV-2 S1 protein solution is supplied PBS pH 7.4.
Stability Protein is shipped on ice packs. Upon arrival, Store at -20°C.Physical Appearance Sterile filtered clear solution.
Purity Protein is >95% pure as determined SDS-PAGE.
Storage Conditions -20ºC
Delivery Details 7-10 days
Special Note(s) For research use ONLY. Not for use on humans.