Product Name: FK-506 (Tacrolimus)
Product Number: INT-3098-PI
Application: Induces Immunosuppression By Inhibiting T Cell Proliferation; Inhibits FKBP12 and Calcineurin (IC50 approx 1 nM); Cell Permeable
Description: FK-506 is cell permeable and induces immunosuppression by inhibiting T cell proliferation. It also inhibits FKBP12 and calcineurin (IC50 approx 1 nM).Solubilization: May be dissolved in DMSO (50 mg/ml); or ethanol (50 mg/ml)
Source: Produced by fermentation
CAS Number: 104987-11-3
Molecular Weight (g/mol): 804
Storage Conditions: -20 °C
Reference(s): D.Y. Yu, et al., IUBMB Life, 58, 429 (2006).
Special Note(s): For research use ONLY. Not for use on humans.