FK-506 (Tacrolimus)

Product Name: FK-506 (Tacrolimus)

Product Number: INT-3098-PI

Synonym(s): Tacrolimus

Application: Induces Immunosuppression By Inhibiting T Cell Proliferation; Inhibits FKBP12 and Calcineurin (IC50 approx 1 nM); Cell Permeable

Description: FK-506 is cell permeable and induces immunosuppression by inhibiting T cell proliferation. It also inhibits FKBP12 and calcineurin (IC50 approx 1 nM).Solubilization: May be dissolved in DMSO (50 mg/ml); or ethanol (50 mg/ml)

Source: Produced by fermentation

CAS Number: 104987-11-3

Molecular Weight (g/mol): 804

Storage Conditions: -20 °C

Reference(s): D.Y. Yu, et al., IUBMB Life, 58, 429 (2006).

Special Note(s): For research use ONLY. Not for use on humans.