omega-Agatoxin IVA (0.1mg vial)

Product Name: omega-Agatoxin IVA (0.1mg vial)

Product Number: PAG-4256-s

Synonym(s): Lys-Lys-Lys-Cys-Ile-Ala-Lys-Asp-Tyr-Gly-Arg-Cys-Lys-Trp-Gly-Gly-Thr-Pro-Cys-Cys-Arg-Gly-Arg-Gly-Cys-Ile-Cys-Ser-Ile-Met-Gly-Thr-Asn-Cys-Glu-Cys-Lys-Pro-Arg-Leu-Ile-Met-Glu-Gly-Leu-Gly-Leu-Ala

Disulfide Bonds: (Disulfide bonds between Cys4-Cys20, Cys12-Cys25, Cys19-Cys36 and Cys27-Cys34)

Application: P-type Ca2+ Channel Selective Blocker

Description: A synthetic Funnel Web Spider toxin

Source: (Funnel Web Spider, Agelenopsis aperta)

Molecular Weight (g/mol): 5202.2

Storage Conditions: -20 °C

Reference(s): I.M. Mintz, V.J. Venema, K.M. Swiderek, T.D. Lee, B.P. Bean, and M.E. Adams, Nature, 355, 827 (1992). (Original) T.J. Turner, M.E. Adams, and K. Dunlap, Science, 258, 310 (1992). (Pharmacol.) H. Nishio, K.Y. Kumagaye, S. Kubo, Y.-N. Chen, A. Momiyama, T. Takahashi, T. Kimura, and S. Sakakibara, Biochem. Biophys. Res. Commun., 196, 1447 (1993). (Chem. Synthesis & Biological Activity) B.M. Olivera, G.P. Miljanich, J. Ramachandran, and M.E. Adams, Annu. Rev. Biochem., 63, 823 (1994). (Review) O.D. Uchitel, Toxicon, 35, 1161 (1997). (Review)

Special Note(s): For research use ONLY. Not for use on humans.