GsMTx-4 (0.1mg vial)

Product Name: GsMTx-4 (0.1mg vial)

Product Number: PCB-4393-s

Synonym(s): H-Gly-Cys-Leu-Glu-Phe-Trp-Trp-Lys-Cys-Asn-Pro-Asn-Asp-Asp-Lys-Cys-Cys-Arg-Pro-Lys-Leu-Lys-Cys-Ser-Lys-Leu-Phe-Lys-Leu-Cys-Asn-Phe-Ser-Phe-NH2

One-Letter-Code: H-GCLEFWWKCNPNDDKCCRPKLKCSKLFKLCNFSF-NH2

Disulfide Bonds: (Disulfide bonds between Cys2-Cys17, Cys9-Cys23, and Cys16-Cys30)

Application: Inhibitor for Cation-Selective Stretch-Activated Channels /Atrial Fibrillation Inhibiting Peptide

Description: A synthetic tarantula spider toxin

Source: (Chilean Rose Tarantula, Grammostola spatulata)

CAS Number: 1209500-46-8

Molecular Weight (g/mol): 4095.8

Storage Conditions: -20 °C

Reference(s): O.P. Hamill and B. Martinac, Physiol. Rev., 81, 685 (2001). (Review; MSCs) T.M. Suchyna, J.H. Johnson, K. Hamer, J.F. Leykam, D.A. Gage, H.F. Clemo, C.M. Baumgarten, and F. Sachs, J. Gen. Physiol., 115, 583 (2000). (Original) K.L. Ostrow, A. Mammoser, T. Suchyna, F. Sachs, R. Oswald, S. Kubo, N. Chino, and P. A. Gottlieb, Toxicon, 42, 263 (2003). (Primary structure; cDNA sequence & Pharmacol.) F. Bode, F. Sachs, and M.R. Franz, Nature, 409, 35 (2001). (Pharmacol.) R.E. Oswald, T.M. Suchyna, R. McFeeters, P. Gottlieb, and F. Sachs, J. Biol. Chem., 277, 34443 (2002). (Solution Structure & S-S Bond)

Special Note(s): For research use ONLY. Not for use on humans.