Calciseptine (0.1mg vial)

Product Name: Calciseptine (0.1mg vial)

Product Number: PCL-4255-s

Synonym(s): Arg-Ile-Cys-Tyr-Ile-His-Lys-Ala-Ser-Leu-Pro-Arg-Ala-Thr-Lys-Thr-Cys-Val-Glu-Asn-Thr-Cys-Tyr-Lys-Met-Phe-Ile-Arg-Thr-Gln-Arg-Glu-Tyr-Ile-Ser-Glu-Arg-Gly-Cys-Gly-Cys-Pro-Thr-Ala-Met-Trp-Pro-Tyr-Gln-Thr-Glu-Cys-Cys-Lys-Gly-Asp-Arg-Cys-Asn-Lys

Disulfide Bonds: (Disulfide bonds are between Cys3-Cys22, Cys17-Cys39, Cys41-Cys52, and Cys53-Cys58)

Application: L-type Ca2+ Channel Blocker

Description: A synthetic snake toxin

Source: (Black mamba, Dendroaspis polylepis polylepis)

CAS Number: 134710-25-1

Molecular Weight (g/mol): 7036.1

Storage Conditions: -20 °C

Reference(s): L-type Ca2+ Channel Blocker J.R. De Weille, H. Schweitz, P. Maes, A. Tartar, and M. Lazdunski, Proc. Natl. Acad. Sci. USA, 88, 2437 (1991). (Original) H. Kuroda, Y.-N. Chen, T.X. Watanabe, T. Kimura, and S. Sakakibara, Pept. Res., 5, 265 (1992). (Chem. Synthesis) T.X. Watanabe, Y. Itahara, H. Kuroda, Y.-N. Chen, T. Kimura, and S. Sakakibara, Jpn. J. Pharmacol., 68, 305 (1995). (Pharmacol.) N. Teramoto, R. Ogata, K. Okabe, A. Kameyama, M. Kameyama, T.X. Watanabe, H. Kuriyama, and K. Kitamura, Pflügers Arch., 432 (1996). (Pharmacol.)

Special Note(s): For research use ONLY. Not for use on humans.