Chlorotoxin (0.5 mg vial)

Product Name: Chlorotoxin (0.5 mg vial)

Product Number: PCN-4282-v

Synonym(s): Met-Cys-Met-Pro-Cys-Phe-Thr-Thr-Asp-His-Gln-Met-Ala-Arg-Lys-Cys-Asp-Asp-Cys-Cys-Gly-Gly-Lys-Gly-Arg-Gly-Lys-Cys-Tyr-Gly-Pro-Gln-Cys-Leu-Cys-Arg-NH2

One-Letter-Code: H-MCMPCFTTDHQMARKCDDCCGGKGRGKCYGPQCLCR-NH2

Disulfide Bonds: (Disulfide bonds between Cys2-Cys19,Cys5-Cys28,Cys16-Cys33 and Cys-Cys35)

Application: Small-Conductance Cl - Channel Blocker

Description: A synthetic scorpion toxin

Source: (Scorpion, Leiurus quinquestriatus)

CAS Number: 163515-35-3

Molecular Weight (g/mol): 3995.7

Storage Conditions: -20 °C

Reference(s): Small-Conductance Cl- Channel Blocker J.A. DeBin, J.E. Maggio, and G.R. Strichartz, Am. J. Physiol., 264, C361 (1993). (Original) J. Najib, P. Sautiere, J.C. Gesquiere, and A. Tartar, In, Innovation and Perspective in Solid Phase Synthesis, (R. Epton, ed.), Mayflower Worldwide, Birmingham, 1994, pp. 615-618. (Original; Amide) G. Lippens, J. Najib, S.J. Wodak, and A. Tartar, Biochemistry, 34, 13 (1995). (NMR Structure) L. Soroceanu, Y. Gillespie, M.B. Khazaeli, and H. Sontheimer, Cancer Res., 58, 4871 (1998). (Pharmacol.)

Special Note(s): For research use ONLY. Not for use on humans.