Mu-Conotoxin SIIIA (0.5 mg vial)

Product Name: Mu-Conotoxin SIIIA (0.5 mg vial)

Product Number: PCN-4440-v

Synonym(s): Pyr-Asn-Cys-Cys-Asn-Gly-Gly-Cys-Ser-Ser-Lys-Trp-Cys-Arg-Asp-His-Ala-Arg-Cys-Cys-NH2

Disulfide Bonds: (Disulfide bonds between Cys3-Cys13, Cys4-Cys19, and Cys8-Cys20)

Application: Tetrodotoxin-Resistant Na+ Channel Blocker with Analgesic Activity

Description: A synthetic cone snail toxin

Source: (Marine Snail, Conus striatus)

Molecular Weight (g/mol): 2207.5

Storage Conditions: -20 °C

Reference(s): G. Bulaj, P.J. West, J.E. Garrett, M. Marsh, M.-M. Zhang, R.S. Norton, B.J. Smith, D. Yoshikami, and B.M. Olivera, Biochemistry, 44, 7259 (2005). (Original; Primary Structure & Pharmacol.) S. Yao, M.-M. Zhang, D. Yoshikami, L. Azam, B.M. Olivera, G. Bulaj, and R.S. Norton, Biochemistry, 47, 10940 (2008). (Solution Structure & Pharmacol.) C.-Z. Wang, H. Zhang, H. Jiang,W. Lu, Z.-Q. Zhao, and C.-W. Chi, Toxicon, 47, 122 (2006). (Pharmacol.) B.R. Green, P. Catlin, M.-M. Zhang, B. Fiedler, W. Bayudan, A. Morrison, R.S. Norton, B.J. Smith, D. Yoshikami, B.M. Olivera, and G. Bulaj, Chem. Biol., 14, 399 (2007). (Pharmacol.)

Special Note(s): For research use ONLY. Not for use on humans.