Dendrotoxin I (0.1mg vial)

Product Name: Dendrotoxin I (0.1mg vial)

Product Number: PDN-4330-s

Synonym(s): Pyr-Pro-Leu-Arg-Lys-Leu-Cys-Ile-Leu-His-Arg-Asp-Pro-Gly-Arg-Cys-Tyr-Gln-Lys-Ile-Pro-Ala-Phe-Tyr-Tyr-Asn-Gln-Lys-Lys-Lys-Gln-Cys-Glu-Gly-Phe-Thr-Trp-Ser-Gly-Cys-Gly-Gly-Asn-Ser-Asn-Arg-Phe-Lys-Thr-Ile-Glu-Glu-Cys-Arg-Arg-Thr-Cys-Ile-Arg-Lys

Disulfide Bonds: (Disulfide bonds between Cys7-Cys57, Cys16-Cys40, and Cys32-Cys53)

Application: Voltage-Dependant K+ Channel Blocker

Description: A synthetic black mamba snake toxin

Source: (Black mamba, Dendroaspis polylepis polylepis)

CAS Number: 107950-33-4

Molecular Weight (g/mol): 7133.2

Storage Conditions: -20 °C

Reference(s): D.J. Strydom, Nature New Biol., 243, 88 (1973). (Original) J.-N. Bidard, C. Mourre, and M. Lazdunski, Biochem. Biophys. Res. Commun., 143, 383 (1987). (Pharmacol.) A.L. Harvey, D.L. Marshall, F.A. De-Allie, and P.N. Strong, Biochem. Biophys. Res. Commun., 163, 394 (1989). (Pharmacol.) H. Nishio, T. Inui, Y. Nishiuchi, C.L.C. De Medeiros, E.G. Rowan, A.L. Harvey, E. Katoh, T. Yamazaki, T. Kimura, and S. Sakakibara, J. Pept. Res., 51, 355 (1998).(Chem. Synthesis & Correction of Sequence; Asp12)

Special Note(s): For research use ONLY. Not for use on humans.