Iberiotoxin (0.1mg vial)

Product Name: Iberiotoxin (0.1mg vial)

Product Number: PIB-4235-s

Synonym(s): Pyr-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-Gln

One-Letter-Code: IbTX

Disulfide Bonds: (Disufide bonds are formed between Cys7-Cys28, Cys13-Cys33, and Cys17-Cys35)

Application: Ca2+-Activated K+ Channel Blocker (Maxi-K+ Channel Blocker)

Description: A synthetic scorpion toxin

Source: (Scorpion, Buthus tamulus)

CAS Number: 129203-60-7

Molecular Weight (g/mol): 4230.8

Storage Conditions: -20 °C

Reference(s): A. Galvez, G. Gimenez-Gallego, J.P. Reuben, L. Roy-Contancin, P. Feigenbaum, G.J. Kaczorowski, and M.L. Garcia, J. Biol. Chem., 265, 11083 (1990). (Original) M.L. Garcia, A. Galvez, M. Garcia-Calvo, V.F. King, J. Vazquez, and G.J. Kaczorowski, J. Bioenerg. Biomembr., 23, 615 (1991). (Review) K.M. Giangiacomo, M.L. Garcia, and O.B. McManus, Biochemistry, 31, 6719 (1992). (Pharmacol.); G.J. Kaczorowski, H.-G. Kaus, R.J. Leonard, O.B. McManus, and M.L. Garcia, J. Bioenerg. Biomembr., 28, 255 (1996). (Review)

Special Note(s): For research use ONLY. Not for use on humans.