Imperatoxin A (0.1mg vial)

Product Name: Imperatoxin A (0.1mg vial)

Product Number: PIM-4343-s

Synonym(s): Gly-Asp-Cys-Leu-Pro-His-Leu-Lys-Arg-Cys-Lys-Ala-Asp-Asn-Asp-Cys-Cys-Gly-Lys-Lys-Cys-Lys-Arg-Arg-Gly-Thr-Asn-Ala-Glu-Lys-Arg-Cys-Arg

One-Letter-Code: IpTXa

Disulfide Bonds: (Disulfide bonds between Cys3-Cys17, Cys10-Cys21, and Cys16-Cys32)

Application: Activator of Ca2+ Release Channels/Ryanodine Receptors

Description: A synthetic scorpion toxin

Source: (Scorpion, Pandinus imperator)

CAS Number: 172451-37-5

Molecular Weight (g/mol): 3758.4

Storage Conditions: -20 °C

Reference(s): H.H. Valdivia, M.S. Kirby, W.J. Lederer, and R.Coronado, Proc. Natl. Acad. Sci. U.S.A., 89, 12185 (1992). (Pharmacol.) R. El-Hayek, A.J. Lokuta, C. Arévalo, and H.H. Valdivia, J. Biol. Chem., 270, 28696 (1995). (Pharmacol.) F.Z. Zamudio, G.B. Gurrola, C. Arévalo, R. Sreekumar, J.W. Walker, H.H. Valdivia, and L.D. Possani, FEBS Lett., 405, 385 (1997). (Original; Structure) K. Takeuchi, J.I. Kim, H. Takahashi, K. Sato, and I. Shimada, Peptide Science, 1999, 307 (2000). (S-S Bond)

Special Note(s): For research use ONLY. Not for use on humans.