Hepcidin / LEAP-1 (Human) (0.1mg vial)

Product Name: Hepcidin / LEAP-1 (Human) (0.1mg vial)

Product Number: PLP-4392-s

Synonym(s): Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr (disulfide bonded), Hepcidin-25


Disulfide Bonds: Reported Disulfide bonds between Cys7-Cys23, Cys10-Cys13, Cys11-Cys19, Cys14-Cys22

Application: Liver-Expressed Antimicrobial Peptide 1 (Human), Liver-Specific Antimicrobial Peptide / Iron-Regulatory Hormone

CAS Number: 342790-21-0

Molecular Weight (g/mol): 2789.4

Storage Conditions: -20 °C

Reference(s): M. Zasloff, Nature, 475, 389 (2002). (Review) A. Krause, et al., FEBS Lett., 480, 147 (2000). (Original; LEAP-1) C.H. Park, E.V. Valore, A.J. Waring, and T. Ganz, J. Biol. Chem., 276, 7806 (2001). (Original; Hepcidin) H.N. Hunter, D.B. Fulton, T. Ganz, and H.J. Vogel, J. Biol. Chem., 277, 37597 (2002). (S-S Bond) R.E. Fleming and W.S. Sly, Proc. Natl. Acad. Sci. USA, 98, 8160 (2001). (Regulation of Iron Homeostasis)

Special Note(s): For research use ONLY. Not for use on humans.