Muscarinic Toxin 3 (0.1mg vial)

Product Name: Muscarinic Toxin 3 (0.1mg vial)

Product Number: PMT-4410-s

Synonym(s): Leu-Thr-Cys-Val-Thr-Lys-Asn-Thr-Ile-Phe-Gly-Ile-Thr-Thr-Glu-Asn-Cys-Pro-Ala-Gly-Gln-Asn-Leu-Cys-Phe-Lys-Arg-Trp-His-Tyr-Val-Ile-Pro-Arg-Tyr-Thr-Glu-Ile-Thr-Arg-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Ile-Pro-Glu-Asn-Tyr-Asp-Ser-Ile-His-Cys-Cys-Lys-Thr-Asp-Lys-Cys-Asn-GluMT3, MTX3, m4-toxin

Disulfide Bonds: (Disulfide bonds between Cys3- Cys24, Cys17- Cys42, Cys46- Cys57, and Cys58- Cys63)

Application: Specific Ligand for Muscarinic Acetylcholine Receptor-4 (M4)

Description: a synthetic snake venom peptide

Source: (Green Mamba, Dendroaspis angusticeps)

Molecular Weight (g/mol): 7379.4

Storage Conditions: -20 °C

Reference(s): M. Jolkkonen, P.L.M. van Giersbergen, U. Hellman, C. Wernstedt, and E. Karlsson, FEBS Lett., 352, 91 (1994). (Original; MT3) J.-S. Liang, J. Carsi-Gabrenas, J.L. Krajewski, J.M. McCafferty, S.L. Purkerson, M.P. Santiago, W.L. Strauss, H.H. Valentine, and L.T. Potter, Toxicon, 34, 1257 (1996). (Original; m4-toxin)A. Adem and E. Karlsson, Life Sci., 60, 1069 (1997) (Pharmacol.; Muscarinic Receptor Subtype Specificity) S. Katayama, M. Ishimaru, H. Nishio, Y. Nishiuchi, and T. Kimura, Peptide Science 2004, 161 (2005). (S-S Bond) Bradley, Pharmacol. Ther., 85, 87 (2000). (Review) L.T. Potter, Life Sci., 68, 2541 (2001). (Review)

Special Note(s): For research use ONLY. Not for use on humans.