Muscarinic Toxin alpha (0.1mg vial)

Product Name: Muscarinic Toxin alpha (0.1mg vial)

Product Number: PMT-4424-s

Synonym(s): Leu-Thr-Cys-Val-Thr-Ser-Lys-Ser-Ile-Phe-Gly-Ile-Thr-Thr-Glu-Asn-Cys-Pro-Asp-Gly-Gln-Asn-Leu-Cys-Phe-Lys-Lys-Trp-Tyr-Tyr-Leu-Asn-His-Arg-Tyr-Ser-Asp-Ile-Thr-Trp-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Lys-Pro-Thr-Asn-Val-Arg-Glu-Thr-Ile-His-Cys-Cys-Glu-Thr-Asp-Lys-Cys-Asn-GluMuscarinic Toxin alpha MTalpha

Disulfide Bonds: (Disulfide bonds between Cys3-Cys24, Cys17-Cys42, Cys46-Cys58, and Cys59-Cys64)

Application: Ligand for Muscarinic Acetylcholine Receptor-3/5 (M3/M5) (Non-specific Ligand)

Description: A synthetic snake toxin

Source: (Black mamba, Dendroaspis polylepis)

Molecular Weight (g/mol): 7545.4

Storage Conditions: -20 °C

Reference(s): M. Jolkkonen, P.L.M. van Giersbergen, U. Hellman, C. Wernstedt, A. Oras, N. Satyapan, A. Adem, and E. Karlsson, Eur. J. Biochem., 234, 579 (1995). (Original; MTalpha) A. Adem and E. Karlsson, Life Sci., 60, 1069 (1997). (Pharmacol.; Muscarinic Receptor Subtype Specificity) M. Jolkkonen, A. Oras, T. Toomela, E. Karlsson, J. Jangstrom¤rv, and K.E.O. angstromkerman, Toxicon, 39, 377 (2001). (Pharmacol.; Mechanism of Receptor Binding)

Special Note(s): For research use ONLY. Not for use on humans.