PLTX-II (0.1mg vial)

Product Name: PLTX-II (0.1mg vial)

Product Number: PPL-4300-s

Synonym(s): Ala-Asp-Cys-Ser-Ala-Thr-Gly-Asp-Thr-Cys-Asp-His-Thr-Lys-Lys-Cys-Cys-Asp-Asp-Cys-Tyr-Thr-Cys-Arg-Cys-Gly-Thr-Pro-Trp-Gly-Ala-Asn-Cys-Arg-Cys-Asp-Tyr-Tyr-Lys-Ala-Arg-Cys-Asp-Thr(Palmitoyl)-NH2

Disulfide Bonds: (Disulfide bonds undetermined)

Application: Presynaptic Ca2+ Channel Blocker

Description: A synthetic spider toxin

Source: (Spider, Plectreurys tristes)

Molecular Weight (g/mol): 5108.7

Storage Conditions: -20 °C

Reference(s): W.D. Branton, L. Kolton, Y.N. Jan, and L.Y. Jan, J. Neurosci., 7, 4195 (1987). (Original) H.-T. Leung, W.D. Branton, H.S. Phillips, L. Jan, and L. Byerly, Neuron, 3, 767 (1989). (Pharmacol.) W.D. Branton, M.S. Rudnick, Y. Zhou, E.D. Eccleston, G.B. Fields, and L.D. Bowers, Nature, 365, 496 (1993). (Thr(Pal)amide) J. Bódi, H. Nishio, Y. Zhou, W.D. Branton, T. Kimura, and S. Sakakibara, Pept. Res., 8, 228 (1995). (Chem. Synthesis & Biological Activity)

Special Note(s): For research use ONLY. Not for use on humans.