Product Name: ProTx-II

Product Number: PTX-3995-PI

Synonym(s): H-Tyr-Cys-Gln-Lys-Trp-Met-Trp-Thr-Cys-Asp-Ser-Glu-Arg-Lys-Cys-Cys-Glu-Gly-Met-Val-Cys-Arg-Leu-Trp-Cys-Lys-Lys-Lys-Leu-Trp-OH; ProTx2

One-Letter-Code: H-YCQKWMWTCDSERKCCEGMVCRLWCKKKLW-OH

Disulfide Bonds: Disulfide bonds between Cys2-Cys16, Cys9-Cys21, and Cys15-Cys25

Application: Na+ Channel (Especially Nav1.7) / Ca2+ Ion Channel Blocker (Gating Modifier)

Description: For a Smaller Quantity in Acetate Form, See PTX-4450-s A spider venom-derived peptide whose sequence is derived from the Tarantula, Thrixopelma pruriens.

Source: Thrixopelma pruriens

Salt Form: Trifluoroacetate Salt

CAS Number: 484598-36-9

Molecular Weight (g/mol): 3826.66

Storage Conditions: -20 °C

Reference(s): R.E. Middleton et al., Biochemistry, 41,14734 (2002). J.J. Smith et al., J. Biol. Chem., 282, 12687 (2007). W. A. Schmalhofer et al., Mol. Pharmacol., 74, 1476 (2008).

Special Note(s): For research use ONLY. Not for use on humans.