Product Name: Ac-Abu-Tle-Leu-Gln-MCA

Product Number: SFP-3250-v

Synonym(s): Ac-Abu-Tle-Leu-Gln-AMC; Acetyl-L-alpha-aminobutyroyl-L-tert-leucyl-L-leucyl-L-glutamine alpha-(4-methylcoumaryl-7-amide)

Application: Fluorescence Substrate for SARS-CoV Mpro/SARS-CoV-2 Mpro Proteases

Description: A fluorogenic substrate targeting the SARS-CoV and SARS-CoV-2 Main Protease (Mpro). The main protease (Mpro­), also called endopeptidase C30 or 3C-like proteinase (3CLpro), controls viral replication activities and is a prime therapeutical target. Both substrates and inhibitors of SARS-CoV-2 Mpro are currently of interest to researchers of the coronavirus.

Source: Fluorogenic Substrate for SARS-CoV/SARS-CoV-2 Mpro

Storage Conditions: -20 °C

Reference(s): W. Rut, K. Groborz, L. Zhang, X. Sun, M. Zmudzinski, R. Hilgenfeld, M. Drag, bioRxiv (2020). DOI: 10.1101/2020.03.07.981928

Special Note(s): For research use ONLY. Not for use on humans.